Assay Detail
Functional
CHEMBL2317112
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Cytotoxicity against wnt-activated human DLD1 cells assessed as cell viability
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DLD-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of 4-phenyl-2-phenylaminopyridine based TNIK inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.89 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2312154 | — | — | 1 | 6.48 |
| CHEMBL2312155 | — | — | 1 | 5.96 |
| CHEMBL2312148 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2312154 | — | IC50 | = | 330.0 | nM | 6.48 |
| CHEMBL2312155 | — | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2312148 | — | IC50 | = | 5800.0 | nM | 5.24 |