Assay Detail
Functional
CHEMBL2317865
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Antiviral activity against Varicella-zoster virus infected in human HFF cells assessed as reduction of viral replication
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human alphaherpesvirus 3 |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
C-3 halo and 3-methyl substituted 5'-nor-3-deazaaristeromycins: synthesis and antiviral properties.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.96 | 6.96 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2312736 | — | — | 1 | 6.96 |
| CHEMBL2312733 | — | — | 1 | - |
| CHEMBL2312734 | — | — | 1 | - |
| CHEMBL2312735 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2312736 | — | EC50 | = | 110.0 | nM | 6.96 |
| CHEMBL2312733 | — | Activity | - | — | - | |
| CHEMBL2312734 | — | EC50 | > | 300000.0 | nM | - |
| CHEMBL2312735 | — | EC50 | > | 60000.0 | nM | - |