Assay Detail
Functional
CHEMBL2318161
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HCT116 cells after 7 days by crystal violet staining based clonogenic assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and inhibitory activities of naringenin derivatives on human colon cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.16 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2312757 | — | — | 1 | 5.92 |
| CHEMBL2312760 | — | — | 1 | 5.72 |
| CHEMBL2312762 | — | — | 1 | 5.36 |
| CHEMBL2312758 | — | — | 1 | 5.22 |
| CHEMBL2312759 | — | — | 1 | 4.80 |
| CHEMBL2312761 | — | — | 1 | 4.70 |
| CHEMBL32571 | — | — | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2312757 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL2312760 | — | IC50 | = | 1910.0 | nM | 5.72 |
| CHEMBL2312762 | — | IC50 | = | 4350.0 | nM | 5.36 |
| CHEMBL2312758 | — | IC50 | = | 6030.0 | nM | 5.22 |
| CHEMBL2312759 | — | IC50 | = | 15870.0 | nM | 4.80 |
| CHEMBL2312761 | — | IC50 | = | 20010.0 | nM | 4.70 |
| CHEMBL32571 | — | IC50 | = | 36750.0 | nM | 4.43 |