Assay Detail
Binding
CHEMBL2318522
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human trypsin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of new cyclic plasmin inhibitors with excellent potency and selectivity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.72 | 8.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2315243 | — | — | 1 | 8.08 |
| CHEMBL2315239 | — | — | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2315243 | — | Ki | = | 8.4 | nM | 8.08 |
| CHEMBL2315239 | — | Ki | = | 44.0 | nM | 7.36 |