Assay Detail
Functional
CHEMBL2318801
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against M-tropic HIV1 Bal virus by cell culture based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Inhibitors of HIV-1 attachment. Part 8: the effect of C7-heteroaryl substitution on the potency, and in vitro and in vivo profiles of indole-based inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.90 | 9.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2315342 | — | — | 1 | 9.43 |
| CHEMBL2315345 | — | — | 1 | 8.12 |
| CHEMBL135339 | — | — | 1 | 6.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2315342 | — | EC50 | = | 0.37 | nM | 9.43 |
| CHEMBL2315345 | — | EC50 | = | 7.61 | nM | 8.12 |
| CHEMBL135339 | — | EC50 | = | 700.0 | nM | 6.16 |