Assay Detail
Binding
CHEMBL2320847
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]-NPY from Y1 receptor in human MCF7 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.33 | 8.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL437027 | BOMBESIN | 1.0 | 1 | 8.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL437027 | BOMBESIN | IC50 | = | 4.7 | nM | 8.33 |