Assay Detail
Binding
CHEMBL2321065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HEPTP (unknown origin) expressed in Escherichia coli using pNPP substrate after 5 mins by spectrophotometric analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Tyrosine-protein phosphatase non-receptor type 7 (CHEMBL2219) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery and evaluation of novel inhibitors of mycobacterium protein tyrosine phosphatase B from the 6-Hydroxy-benzofuran-5-carboxylic acid scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.63 | 5.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2316907 | — | — | 1 | 5.72 |
| CHEMBL2316902 | — | — | 1 | 5.68 |
| CHEMBL2316906 | — | — | 1 | 5.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2316907 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL2316902 | — | IC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL2316906 | — | IC50 | = | 3300.0 | nM | 5.48 |