Assay Detail
Binding
CHEMBL2328064
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Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
High-Throughput Selectivity Assays for Small-Molecule Inhibitors of β-Catenin/T-Cell Factor Protein-Protein Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 4.98 | 5.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL578512 | — | — | 1 | 5.43 |
| CHEMBL2323032 | — | — | 1 | 5.42 |
| CHEMBL2323033 | — | — | 1 | 5.23 |
| CHEMBL2323029 | — | — | 1 | 4.89 |
| CHEMBL2323028 | — | — | 1 | 4.68 |
| CHEMBL2323031 | — | — | 1 | 4.68 |
| CHEMBL2323030 | — | — | 1 | 4.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL578512 | — | Ki | = | 3700.0 | nM | 5.43 |
| CHEMBL2323032 | — | Ki | = | 3800.0 | nM | 5.42 |
| CHEMBL2323033 | — | Ki | = | 5900.0 | nM | 5.23 |
| CHEMBL2323029 | — | Ki | = | 13000.0 | nM | 4.89 |
| CHEMBL2323028 | — | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL2323031 | — | Ki | = | 21000.0 | nM | 4.68 |
| CHEMBL2323030 | — | Ki | = | 29000.0 | nM | 4.54 |