Compound Detail
CHEMBL2323030
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2323030 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WBJNKIGKWHXRGD-DHZHZOJOSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
353.4
MW (Da)
2.38
ALogP
6
HBA
1
HBD
76.1
PSA (Ų)
0.62
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 3 meas. best 4.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| TCF4/beta-catenin CHEMBL3038511 | Ki | 4.54 | 4.54 | 29000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| TCF4/beta-catenin | Ki | = | 29000.0 | nM | 4.54 | Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay | 24900664 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24900664 | 10.1021/ml300367f | Unchecked | 2 |
| 24900664 | 10.1021/ml300367f | Adenomatous polyposis coli protein/Transcription factor 7-like 2 | 1 |
| 24900664 | 10.1021/ml300367f | Cadherin-1/Transcription factor 7-like 2 | 1 |
| 24900664 | 10.1021/ml300367f | TCF4/beta-catenin | 1 |
| 35581674 | 10.1021/acs.jmedchem.2c00228 | Catenin beta-1 | 1 |
Data from ChEMBL 36 via Core Engine