Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2328683

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]Nalpha-methylhistamine from human recombinant histamine H3 receptor expressed in HEK-293 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK293
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Histamine H3 receptor (CHEMBL264)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Bodilisant-a novel fluorescent, highly affine histamine h3 receptor ligand.
Tomasch M, Schwed JS, Paulke A, Stark H.
ACS Med Chem Lett (2013) 4 : 269 -273
PubMed 24900647 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 7.77 8.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2323582 BODILISANT 1 8.19
CHEMBL14638 CIPROXIFAN 1 7.34

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2323582 BODILISANT Ki = 6.51 nM 8.19
CHEMBL14638 CIPROXIFAN Ki = 46.0 nM 7.34