Assay Detail
Binding
CHEMBL2329346
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Inhibition of human recombinant ACC1
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Treatment of Obesity and Related Disorders with Acetyl-CoA Carboxylase Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 8.21 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2323626 | — | — | 1 | 8.66 |
| CHEMBL2323628 | — | — | 1 | 8.30 |
| CHEMBL2323629 | — | — | 1 | 7.96 |
| CHEMBL2323627 | — | — | 1 | 7.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2323626 | — | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL2323628 | — | IC50 | = | 5.0 | nM | 8.30 |
| CHEMBL2323629 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL2323627 | — | IC50 | = | 12.0 | nM | 7.92 |