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Assay Detail

CHEMBL2330506

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HL60 cells assessed as inhibition of cell proliferation after 96 hrs
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HL-60
Confidence 1 — Organism
Curated By Autocuration

Target

HL-60 (CHEMBL383)
Type CELL-LINE
Organism Homo sapiens

Publication

Design, synthesis, and biological evaluation of indenoisoquinoline rexinoids with chemopreventive potential.
Conda-Sheridan M, Park EJ, Beck DE, Reddy PV, Nguyen TX, Hu B, Chen L, White JJ, van Breemen RB, Pezzuto JM, Cushman M.
J Med Chem (2013) 56 : 2581 -2605
PubMed 23472886 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.04 7.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2172212 1 7.04

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2172212 IC50 = 92.0 nM 7.04