Assay Detail
Binding
CHEMBL2330587
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human neuraminidase 3 expressed in Escherichia coli using 4MU-NANA as substrate measured for every 30 seconds for 60 mins by fluorescence assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.24 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | — | 1 | 5.66 |
| CHEMBL2325811 | — | — | 1 | 5.10 |
| CHEMBL2325813 | — | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96712 | NEU5AC2EN | Ki | = | 2200.0 | nM | 5.66 |
| CHEMBL2325811 | — | Ki | = | 8000.0 | nM | 5.10 |
| CHEMBL2325813 | — | Ki | = | 11000.0 | nM | 4.96 |