Assay Detail
Binding
CHEMBL2330673
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Binding affinity to Pseudomonas putida KSI by isothermal titration calorimetry
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas putida |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Incorporation of rapid thermodynamic data in fragment-based drug discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 4.34 | 4.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL406393 | DEOXYCHOLIC ACID | 4.0 | 1 | 4.80 |
| CHEMBL1499599 | — | — | 1 | 4.66 |
| CHEMBL1338939 | — | — | 1 | 4.34 |
| CHEMBL107281 | — | — | 1 | 4.30 |
| CHEMBL382602 | — | — | 1 | 4.20 |
| CHEMBL2322559 | — | — | 1 | 3.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL406393 | DEOXYCHOLIC ACID | Kd | = | 16000.0 | nM | 4.80 |
| CHEMBL1499599 | — | Kd | = | 22000.0 | nM | 4.66 |
| CHEMBL1338939 | — | Kd | = | 46000.0 | nM | 4.34 |
| CHEMBL107281 | — | Kd | = | 50000.0 | nM | 4.30 |
| CHEMBL382602 | — | Kd | = | 63000.0 | nM | 4.20 |
| CHEMBL2322559 | — | Kd | = | 180000.0 | nM | 3.75 |