Assay Detail

CHEMBL2339935

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Functional

Cytotoxicity against human HL60 cells

ChEMBL ↗

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Target

HL-60 (CHEMBL383) ↗

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Primary target HL-60

CHEMBL383

Anchored from Assay target.

Protein identity HL-60

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	HL-60
Confidence	1 — Organism
Curated By	Autocuration

Target

HL-60 (CHEMBL383) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Alkyl esters of gallic acid as anticancer agents: a review.

Locatelli C, Filippin-Monteiro FB, Filippin-Monteiro FB, Creczynski-Pasa TB.
Eur J Med Chem (2013) 60 : 233 -239
PubMed 23291333 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	3	4.48	4.48

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL16121	DODECYL GALLATE	—	1	4.48
CHEMBL7983	PROPYL GALLATE	1.0	1	-
CHEMBL288114	GALLIC ACID	2.0	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL16121	DODECYL GALLATE	IC50	=	33000.0	nM	4.48
CHEMBL7983	PROPYL GALLATE	IC50		-	—	-
CHEMBL288114	GALLIC ACID	IC50	=	300000.0	nM	-