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Assay Detail

CHEMBL2339938

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Staphylococcus aureus RN6390B Agr-mediated RNA3 promoter activation measured up to 6 hrs by Northern blot analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Accessory gene regulator protein A (CHEMBL1681616)
Type SINGLE PROTEIN
Organism Staphylococcus aureus

Publication

Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.
Gordon CP, Williams P, Chan WC.
J Med Chem (2013) 56 : 1389 -1404
PubMed 23294220 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.22 5.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8483 1 5.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8483 IC50 = 6000.0 nM 5.22