Assay Detail
Binding
CHEMBL2340978
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Inhibition of AChE (unknown origin)
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structural analogs of huperzine A improve survival in guinea pigs exposed to soman.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| INH | 2 | - | - |
| IC50 | 1 | 7.35 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395280 | HUPERZINE A | 2.0 | 1 | 7.35 |
| CHEMBL2333849 | — | — | 1 | - |
| CHEMBL2333848 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395280 | HUPERZINE A | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL2333849 | — | INH | = | 10.0 | uM | - |
| CHEMBL2333848 | — | INH | = | 5.0 | uM | - |