Assay Detail

CHEMBL2343199

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ADMET

Cytotoxicity against human HEK293 cells assessed as cell survival by SRB assay

ChEMBL ↗

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Target

HEK293 (CHEMBL614818) ↗

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Primary target HEK293

CHEMBL614818

Anchored from Assay target.

Protein identity HEK293

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	ADMET
Organism	Homo sapiens
Cell Type	HEK293
Confidence	1 — Organism
Curated By	Autocuration

Target

HEK293 (CHEMBL614818) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Biologically active withanolides from Withania coagulans.

Ihsan-ul-Haq, Youn UJ, Chai X, Park EJ, Kondratyuk TP, Simmons CJ, Borris RP, Mirza B, Pezzuto JM, Chang LC.
J Nat Prod (2013) 76 : 22 -28
PubMed 23316950 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	5.42	5.42

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL60718	TPCK	—	1	5.42

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL60718	TPCK	IC50	=	3800.0	nM	5.42