HEK293 · CELL-LINE · Homo sapiens
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Confirm a stable target identifier before relying on this context across project surfaces.
HEK293
Review this target as HEK293.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats HEK293 as ChEMBL target CHEMBL614818. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | HEK293 |
| Target Type | CELL-LINE |
| Organism | Homo sapiens |
Reviewable protein naming and mapping context for this target snapshot.
Review this target as HEK293.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4794117 | 10.52 | IC50 | 0.03 | Preclinical |
| CHEMBL4800456 | 10.1 | IC50 | 0.08 | Preclinical |
| CHEMBL3822907 | 9.89 | IC50 | 0.1278 | Preclinical |
| CHEMBL15177 | 9.8 | IC50 | 0.16 | Preclinical |
| CHEMBL4094083 | 9.77 | IC50 | 0.17 | Preclinical |
| CHEMBL4075161 | 9.64 | IC50 | 0.23 | Preclinical |
| CHEMBL4066549 | 9.62 | IC50 | 0.242 | Preclinical |
| CHEMBL139702 | 9.55 | IC50 | 0.28 | Preclinical |
| CHEMBL3823024 | 9.51 | IC50 | 0.3065 | Preclinical |
| CHEMBL469912 | 9.46 | IC50 | 0.35 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 1,251 | 1,893 | 5.2 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 864 | 1,490 | 5.4 |
| organism-based format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 454 | 381 | 5.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 15 | 35 | 5.8 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| cell-based format | 8 | 0 | — |