Assay Detail
Binding
CHEMBL2343230
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Binding affinity to Pseudomonas aeruginosa apo Heme oxygenase expressed in Escherichia coli BL21(DE3) assessed as decrease in tryptophan fluorescence
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Small molecule antivirulents targeting the iron-regulated heme oxygenase (HemO) of P. aeruginosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 4.59 | 4.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL395102 | — | — | 1 | 4.74 |
| CHEMBL1713547 | — | — | 1 | 4.53 |
| CHEMBL244625 | — | — | 1 | 4.51 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL395102 | — | Kd | = | 18400.0 | nM | 4.74 |
| CHEMBL1713547 | — | Kd | = | 29300.0 | nM | 4.53 |
| CHEMBL244625 | — | Kd | = | 31200.0 | nM | 4.51 |