Assay Detail
Functional
CHEMBL2343263
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human CEM cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CCRF-CEM |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of 2-(alkoxycarbonyl)-3-anilinobenzo[b]thiophenes and thieno[2,3-b]pyridines as new potent anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.58 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | 4.0 | 1 | 8.70 |
| CHEMBL2332030 | — | — | 1 | 8.55 |
| CHEMBL2332025 | — | — | 1 | 8.49 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL159 | VINBLASTINE | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL2332030 | — | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL2332025 | — | IC50 | = | 3.2 | nM | 8.49 |