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Assay Detail

CHEMBL2343634

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human NFF cells assessed as inhibition of cell viability after 72 hrs by alamar blue assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NFF
Confidence 1 — Organism
Curated By Autocuration

Target

NFF (CHEMBL614198)
Type CELL-LINE
Organism Homo sapiens

Publication

Bromotyrosine alkaloids from the Australian marine sponge Pseudoceratina verrucosa.
Tran TD, Pham NB, Fechner G, Hooper JN, Quinn RJ.
J Nat Prod (2013) 76 : 516 -523
PubMed 23489291 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 6.29 7.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL501867 VINCRISTINE SULFATE 4.0 1 7.77
CHEMBL2332123 1 4.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL501867 VINCRISTINE SULFATE IC50 = 16.9 nM 7.77
CHEMBL2332123 IC50 = 16000.0 nM 4.80