Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL2344592

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as concentration required for 50 % inhibition of micoM DPPH activity after 30 mins by UV-vis spectrophotometry
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 1 — Organism
Curated By Autocuration

Publication

Fungal metabolites of xanthohumol with potent antiproliferative activity on human cancer cell lines in vitro.
Tronina T, Bartmańska A, Filip-Psurska B, Wietrzyk J, Popłoński J, Huszcza E.
Bioorg Med Chem (2013) 21 : 2001 -2006
PubMed 23434138 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 10 5.35 6.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2337361 1 6.64
CHEMBL196 ASCORBIC ACID 4.0 1 6.28
CHEMBL253896 XANTHOHUMOL 2.0 1 5.70
CHEMBL2337358 1 5.65
CHEMBL479500 XANTHOHUMOL D 1 5.62
CHEMBL470927 XANTHOHUMOL H 1 5.48
CHEMBL510279 DIHYDROXANTHOHUMOL 1 4.89
CHEMBL2337359 1 4.69
CHEMBL492828 ISOXANTHOHUMOL 1 4.45
CHEMBL2337360 1 4.06

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2337361 IC50 = 230.0 nM 6.64
CHEMBL196 ASCORBIC ACID IC50 = 520.0 nM 6.28
CHEMBL253896 XANTHOHUMOL IC50 = 1980.0 nM 5.70
CHEMBL2337358 IC50 = 2240.0 nM 5.65
CHEMBL479500 XANTHOHUMOL D IC50 = 2370.0 nM 5.62
CHEMBL470927 XANTHOHUMOL H IC50 = 3340.0 nM 5.48
CHEMBL510279 DIHYDROXANTHOHUMOL IC50 = 12970.0 nM 4.89
CHEMBL2337359 IC50 = 20440.0 nM 4.69
CHEMBL492828 ISOXANTHOHUMOL IC50 = 35420.0 nM 4.45
CHEMBL2337360 IC50 = 87370.0 nM 4.06