Assay Detail
Binding
CHEMBL2345554
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Inhibition of TIE2 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Trimeric hemibastadin congener from the marine sponge Ianthella basta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.02 | 6.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2333163 | SESQUIBASTADIN 1 | — | 1 | 6.22 |
| CHEMBL505637 | BASTADIN 3 | — | 1 | 6.10 |
| CHEMBL360190 | BASTADIN 7 | — | 1 | 5.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2333163 | SESQUIBASTADIN 1 | IC50 | = | 600.0 | nM | 6.22 |
| CHEMBL505637 | BASTADIN 3 | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL360190 | BASTADIN 7 | IC50 | = | 1800.0 | nM | 5.75 |