Assay Detail
Binding
CHEMBL2345556
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SAK (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase PLK4 (CHEMBL3788) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Trimeric hemibastadin congener from the marine sponge Ianthella basta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.76 | 6.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2333163 | SESQUIBASTADIN 1 | — | 1 | 6.16 |
| CHEMBL360190 | BASTADIN 7 | — | 1 | 5.72 |
| CHEMBL505637 | BASTADIN 3 | — | 1 | 5.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2333163 | SESQUIBASTADIN 1 | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL360190 | BASTADIN 7 | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL505637 | BASTADIN 3 | IC50 | = | 4100.0 | nM | 5.39 |