Assay Detail
Binding
CHEMBL2345558
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDGFR-beta (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Platelet-derived growth factor receptor beta (CHEMBL1913) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Trimeric hemibastadin congener from the marine sponge Ianthella basta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.29 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL505637 | BASTADIN 3 | — | 1 | 5.48 |
| CHEMBL2333163 | SESQUIBASTADIN 1 | — | 1 | 5.40 |
| CHEMBL360190 | BASTADIN 7 | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL505637 | BASTADIN 3 | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL2333163 | SESQUIBASTADIN 1 | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL360190 | BASTADIN 7 | IC50 | = | 10200.0 | nM | 4.99 |