Assay Detail
Functional
CHEMBL2345704
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against mouse Colon 26 cells assessed as inhibition of cell growth
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Colon 26 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biochemical activities of antiproliferative amino acid and phosphate derivatives of microtubule-disrupting β-lactam combretastatins.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.06 | 8.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL330407 | — | — | 1 | 8.55 |
| CHEMBL572284 | OMBRABULIN | 3.0 | 1 | 7.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL330407 | — | IC50 | = | 2.8 | nM | 8.55 |
| CHEMBL572284 | OMBRABULIN | IC50 | = | 27.2 | nM | 7.57 |