Assay Detail
Binding
CHEMBL2350000
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human thrombin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing methyl ferulate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.35 | 8.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL539697 | DABIGATRAN ETEXILATE | 4.0 | 1 | 8.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL539697 | DABIGATRAN ETEXILATE | Ki | = | 4.5 | nM | 8.35 |