Assay Detail
Binding
CHEMBL2350640
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant full length human NNMT measured for 30 mins by SAHH-coupled fluorescence assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bromo-deaza-SAH: a potent and selective DOT1L inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.12 | 6.12 |
| IC50 | 1 | 5.82 | 5.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2349526 | — | — | 2 | 6.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2349526 | — | Ki | = | 750.0 | nM | 6.12 |
| CHEMBL2349526 | — | IC50 | = | 1500.0 | nM | 5.82 |