Assay Detail
Functional
CHEMBL2350893
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Anti-neuroinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.37 | 4.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL463337 | — | — | 1 | 4.37 |
| CHEMBL2349422 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL463337 | — | IC50 | = | 42870.0 | nM | 4.37 |
| CHEMBL2349422 | — | IC50 | = | 174890.0 | nM | - |