Assay Detail
Functional
CHEMBL2353201
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Inhibition of PMA induced ROS generation in human HL60 cells assessed as inhibition of ROA mediated oxidation of DCFH
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.17 | 5.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL153 | TROLOX | — | 1 | 5.85 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | — | 1 | 4.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL153 | TROLOX | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL44509 | (E)-3,4,3',5'-TETRAMETHOXYSTILBENE | IC50 | = | 33300.0 | nM | 4.48 |