Assay Detail
ADMET
CHEMBL2353432
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Cytotoxicity against mouse NIH/3T3 cells at 1 to 30 uM after 72 hrs by resazurin assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Guanidino anthrathiophenediones as G-quadruplex binders: uptake, intracellular localization, and anti-Harvey-Ras gene activity in bladder cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.70 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2349418 | — | — | 1 | 4.70 |
| CHEMBL472033 | — | — | 1 | 4.70 |
| CHEMBL2349420 | — | — | 1 | - |
| CHEMBL2349419 | — | — | 1 | - |
| CHEMBL2349417 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2349418 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL472033 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL2349420 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2349419 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2349417 | — | IC50 | > | 30000.0 | nM | - |