Assay Detail
Functional
CHEMBL2354243
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PubChem BioAssay. Dose response counterscreen for EBI2 assay utilizing the enzyme, b-galactosidase. (Class of assay: confirmatory)
280
Total Activities
280
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 280 | 5.27 | 7.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1576301 | — | — | 1 | 7.17 |
| CHEMBL1560839 | — | — | 1 | 6.62 |
| CHEMBL2001888 | — | — | 1 | 6.37 |
| CHEMBL1563728 | — | — | 1 | 6.31 |
| CHEMBL1358406 | — | — | 1 | 6.10 |
| CHEMBL1359506 | — | — | 1 | 6.04 |
| CHEMBL1973773 | — | — | 1 | 5.91 |
| CHEMBL1891367 | — | — | 1 | 5.59 |
| CHEMBL1986765 | — | — | 1 | 5.10 |
| CHEMBL1719799 | — | — | 1 | 4.41 |
| CHEMBL1309171 | — | — | 1 | 4.18 |
| CHEMBL3212216 | — | — | 1 | 4.18 |
| CHEMBL1722821 | — | — | 1 | 4.14 |
| CHEMBL1476643 | — | — | 1 | 4.11 |
| CHEMBL3198149 | — | — | 1 | 4.11 |
| CHEMBL3191079 | — | — | 1 | 4.02 |
| CHEMBL1477073 | — | — | 1 | - |
| CHEMBL2138050 | — | — | 1 | - |
| CHEMBL1447703 | — | — | 1 | - |
| CHEMBL1542947 | — | — | 1 | - |
| CHEMBL1521405 | — | — | 1 | - |
| CHEMBL1437887 | — | — | 1 | - |
| CHEMBL1604425 | — | — | 1 | - |
| CHEMBL2359091 | — | — | 1 | - |
| CHEMBL1371329 | — | — | 1 | - |
| CHEMBL1497259 | — | — | 1 | - |
| CHEMBL1323953 | — | — | 1 | - |
| CHEMBL1516503 | — | — | 1 | - |
| CHEMBL1346409 | — | — | 1 | - |
| CHEMBL1493465 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1576301 | — | IC50 | = | 68.1 | nM | 7.17 |
| CHEMBL1560839 | — | IC50 | = | 239.0 | nM | 6.62 |
| CHEMBL2001888 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL1563728 | — | IC50 | = | 485.0 | nM | 6.31 |
| CHEMBL1358406 | — | IC50 | = | 791.0 | nM | 6.10 |
| CHEMBL1359506 | — | IC50 | = | 904.0 | nM | 6.04 |
| CHEMBL1973773 | — | IC50 | = | 1230.0 | nM | 5.91 |
| CHEMBL1891367 | — | IC50 | = | 2540.0 | nM | 5.59 |
| CHEMBL1986765 | — | IC50 | = | 7970.0 | nM | 5.10 |
| CHEMBL1719799 | — | IC50 | = | 39200.0 | nM | 4.41 |
| CHEMBL1309171 | — | IC50 | = | 66100.0 | nM | 4.18 |
| CHEMBL3212216 | — | IC50 | = | 65900.0 | nM | 4.18 |
| CHEMBL1722821 | — | IC50 | = | 71600.0 | nM | 4.14 |
| CHEMBL3198149 | — | IC50 | = | 77500.0 | nM | 4.11 |
| CHEMBL1476643 | — | IC50 | = | 77500.0 | nM | 4.11 |
| CHEMBL3191079 | — | IC50 | = | 96000.0 | nM | 4.02 |
| CHEMBL2362691 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1485019 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1300035 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1383320 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1468767 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1383436 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1597123 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1974230 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1390055 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1875381 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1406060 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1708006 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1728042 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1967155 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1558203 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1596775 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1436264 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1558970 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1731619 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1372778 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1402279 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1509254 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1391324 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1352375 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1602482 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1570834 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL3193792 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1391188 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1402203 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL2143103 | — | IC50 | = | 121000.0 | nM | - |
| CHEMBL1878561 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1558844 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL3213414 | — | IC50 | > | 80000.0 | nM | - |
| CHEMBL1398286 | — | IC50 | > | 80000.0 | nM | - |