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Compound Detail

CHEMBL1967155

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CCOC(=O)c1ccc(/N=c2\sc(C(=O)OC)cc(=O)n2CCCN2CCOCC2)cc1

Basic Information

ChEMBL ID CHEMBL1967155
Phase Preclinical
Structure Type MOL
InChI Key CYPRETKROIGJNW-FCQUAONHSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

461.5
MW (Da)
1.83
ALogP
10
HBA
0
HBD
99.4
PSA (Ų)
0.55
QED
0
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H27N3O6S
MW 461.54
Aromatic Rings 2
Heavy Atoms 32
NP-Likeness -1.41

Activity Summary

IC50 2 meas. best 5.34

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.34 5.19 4520.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine