Assay Detail
ADMET
CHEMBL2379099
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Antiproliferative activity against human LEP-3 cells after 24 hrs by MTS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | LEP-3 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis and antiproliferative properties of some new 5-substituted-2-iminobenzimidazole derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 7.77 | 9.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2377274 | — | — | 1 | 9.68 |
| CHEMBL2377275 | — | — | 1 | 7.91 |
| CHEMBL2377272 | — | — | 1 | 7.17 |
| CHEMBL2377273 | — | — | 1 | 7.14 |
| CHEMBL2377271 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2377274 | — | EC50 | = | 0.21 | nM | 9.68 |
| CHEMBL2377275 | — | EC50 | = | 12.2 | nM | 7.91 |
| CHEMBL2377272 | — | EC50 | = | 68.0 | nM | 7.17 |
| CHEMBL2377273 | — | EC50 | = | 73.0 | nM | 7.14 |
| CHEMBL2377271 | — | EC50 | = | 114.0 | nM | 6.94 |