Assay Detail
ADMET
CHEMBL2379299
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Cytotoxicity against mouse NIH/3T3 cells after 24 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytotoxic 3,4,5-trimethoxychalcones as mitotic arresters and cell migration inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.75 | 8.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 8.59 |
| CHEMBL220818 | — | — | 1 | 4.47 |
| CHEMBL285901 | — | — | 1 | 4.18 |
| CHEMBL1946988 | — | — | 1 | - |
| CHEMBL484145 | — | — | 1 | - |
| CHEMBL7976 | CHALCONE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107 | COLCHICINE | IC50 | = | 2.6 | nM | 8.59 |
| CHEMBL220818 | — | IC50 | = | 34000.0 | nM | 4.47 |
| CHEMBL285901 | — | IC50 | = | 66000.0 | nM | 4.18 |
| CHEMBL1946988 | — | IC50 | - | — | - | |
| CHEMBL484145 | — | IC50 | - | — | - | |
| CHEMBL7976 | CHALCONE | IC50 | - | — | - |