Assay Detail
Binding
CHEMBL2379560
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Inhibition of FAAH (unknown origin)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
(4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.93 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL175854 | — | — | 1 | 9.00 |
| CHEMBL184238 | URB-597 | 1.0 | 1 | 8.42 |
| CHEMBL2171700 | — | — | 1 | 7.19 |
| CHEMBL570812 | — | — | 1 | 7.12 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL175854 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL184238 | URB-597 | IC50 | = | 3.8 | nM | 8.42 |
| CHEMBL2171700 | — | IC50 | = | 65.0 | nM | 7.19 |
| CHEMBL570812 | — | IC50 | = | 76.0 | nM | 7.12 |