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Assay Detail

CHEMBL2379629

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of AChE (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Acetylcholinesterase (CHEMBL220)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of novel 2,6-disubstituted pyridazinone derivatives as acetylcholinesterase inhibitors.
Xing W, Fu Y, Shi Z, Lu D, Zhang H, Hu Y.
Eur J Med Chem (2013) 63 : 95 -103
PubMed 23466605 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL32823 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL32823 IC50 = 0.4 nM 9.40