Assay Detail
ADMET
CHEMBL2380025
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human YCC-3/D cells after 36 hrs by MTS assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | YCC-3/D |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
In silico identification of poly(ADP-ribose)polymerase-1 inhibitors and their chemosensitizing effects against cisplatin-resistant human gastric cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.02 | 4.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL249813 | — | — | 1 | 4.02 |
| CHEMBL2377258 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL249813 | — | IC50 | = | 96320.0 | nM | 4.02 |
| CHEMBL2377258 | — | IC50 | > | 200000.0 | nM | - |