Assay Detail
Binding
CHEMBL2380131
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mouse brain MAO-B
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A comprehensive review on synthesis and designing aspects of coumarin derivatives as monoamine oxidase inhibitors for depression and Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.54 | 4.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL567517 | LACINARTIN | — | 1 | 4.54 |
| CHEMBL307341 | AURAPTENE | — | 1 | - |
| CHEMBL2346911 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL567517 | LACINARTIN | IC50 | = | 28600.0 | nM | 4.54 |
| CHEMBL307341 | AURAPTENE | IC50 | = | 0.0006 | nM | - |
| CHEMBL2346911 | — | IC50 | = | 0.0005 | nM | - |