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Assay Detail

CHEMBL2390328

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type RAW264.7
Confidence 1 — Organism
Curated By Autocuration

Target

RAW264.7 (CHEMBL612557)
Type CELL-LINE
Organism Mus musculus

Publication

Anti-inflammatory secondary metabolites from the leaves of Rosa laevigata.
Yan M, Zhu Y, Zhang HJ, Jiao WH, Han BN, Liu ZX, Qiu F, Chen WS, Lin HW.
Bioorg Med Chem (2013) 21 : 3290 -3297
PubMed 23632365 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.98 4.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2385208 1 4.98

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2385208 IC50 = 10380.0 nM 4.98