Assay Detail
Binding
CHEMBL2390473
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of human AMPK alpha2 (1 to 398) expressed in African green monkey COS7 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS-7 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
5'-AMP-activated protein kinase catalytic subunit alpha-2 (CHEMBL2116) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase Activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.92 | 4.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1242297 | — | — | 1 | 4.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1242297 | — | EC50 | = | 12000.0 | nM | 4.92 |