Assay Detail
Binding
CHEMBL2390664
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to amyloid beta (1 to 40) (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress and developments in tau aggregation inhibitors for Alzheimer disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.88 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL207456 | PITTSBURGH COMPOUND B | 2.0 | 1 | 7.70 |
| CHEMBL224392 | THIOFLAVIN T | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL207456 | PITTSBURGH COMPOUND B | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL224392 | THIOFLAVIN T | Ki | = | 890.0 | nM | 6.05 |