Assay Detail
Binding
CHEMBL2394433
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KCa2.3 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Small conductance calcium-activated potassium channel protein 3 (CHEMBL3381) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Further studies on bis-charged tetraazacyclophanes as potent inhibitors of small conductance Ca(2+)-activated K+ channels.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.37 | 7.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3040285 | — | — | 1 | 7.51 |
| CHEMBL360621 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3040285 | — | IC50 | = | 31.0 | nM | 7.51 |
| CHEMBL360621 | — | IC50 | = | 60.0 | nM | 7.22 |