Assay Detail
Binding
CHEMBL2394944
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to human NK3 receptor by radioligand displacement assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.42 | 8.42 |
| IC50 | 1 | 8.15 | 8.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL10284 | SB-222200 | — | 2 | 8.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL10284 | SB-222200 | Ki | = | 3.8 | nM | 8.42 |
| CHEMBL10284 | SB-222200 | IC50 | = | 7.1 | nM | 8.15 |