Assay Detail
Binding
CHEMBL2395266
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]CGP54626 from human recombinant GABAB1A receptor expressed in CHO cells after 3 hrs
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Gamma-aminobutyric acid type B receptor subunit 1 (CHEMBL2064) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.54 | 8.54 |
| IC50 | 1 | 8.19 | 8.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2391908 | — | — | 2 | 8.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2391908 | — | Ki | = | 2.9 | nM | 8.54 |
| CHEMBL2391908 | — | IC50 | = | 6.4 | nM | 8.19 |