Assay Detail
Functional
CHEMBL2399043
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Antiviral activity against Poliovirus assessed as protection against virus-induced cytopathic effect by cell-based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Poliovirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and biological evaluation of novel aminothiazoles as antiviral compounds acting against human rhinovirus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 6.33 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2397316 | — | — | 1 | 6.89 |
| CHEMBL2397315 | — | — | 1 | 6.55 |
| CHEMBL2397314 | — | — | 1 | 5.96 |
| CHEMBL2397317 | — | — | 1 | 5.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2397316 | — | EC50 | = | 130.0 | nM | 6.89 |
| CHEMBL2397315 | — | EC50 | = | 280.0 | nM | 6.55 |
| CHEMBL2397314 | — | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL2397317 | — | EC50 | = | 1200.0 | nM | 5.92 |