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Assay Detail

CHEMBL2400340

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human HCT116 cells assessed as cell survival at 0.5 to 5 uM after 7 days by crystal violet staining assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HCT-116
Confidence 1 — Organism
Curated By Autocuration

Target

HCT-116 (CHEMBL394)
Type CELL-LINE
Organism Homo sapiens

Publication

Chromenylchalcones showing cytotoxicity on human colon cancer cell lines and in silico docking with aurora kinases.
Shin SY, Yoon H, Ahn S, Kim DW, Kim SH, Koh D, Lee YH, Lim Y.
Bioorg Med Chem (2013) 21 : 4250 -4258
PubMed 23719279 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.01 7.01

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2396883 1 7.01

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2396883 IC50 = 96.7 nM 7.01