Assay Detail
Functional
CHEMBL2400556
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimigratory activity against human DLD1 cells overexpressing PRL3 by crystal violet staining-based light microscopic analysis
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DLD-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.23 | 5.30 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2397162 | — | — | 2 | 5.30 |
| CHEMBL207958 | — | — | 2 | 5.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2397162 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL207958 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL2397162 | — | Inhibition | - | % | - | |
| CHEMBL207958 | — | Inhibition | - | % | - |