Assay Detail
Binding
CHEMBL2404445
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at serotonin 5HT2B receptor (unknown origin) by PDSP assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 6.42 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL481153 | — | — | 1 | 7.00 |
| CHEMBL240045 | — | — | 1 | 6.77 |
| CHEMBL519609 | — | — | 1 | 6.20 |
| CHEMBL241115 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL481153 | — | Ki | = | 100.0 | nM | 7.00 |
| CHEMBL240045 | — | Ki | = | 170.0 | nM | 6.77 |
| CHEMBL519609 | — | Ki | = | 630.0 | nM | 6.20 |
| CHEMBL241115 | — | Ki | = | 2000.0 | nM | 5.70 |